Time-scales in the interplay between calcium and voltage dynamics
نویسندگان
چکیده
The interaction between slow calcium dynamics and voltage dynamics increases the processing capabilities of neurons. A proper understanding of this interaction has to take into account its stochastic nature. We recorded voltage and calcium from spiking–bursting neurons and performed a statistical study of the correlation between both variables. We found a rich repertoire of time scales and correlated and uncorrelated parameters. We expect our results to constrain future modelling of spike bursting. r 2006 Elsevier B.V. All rights reserved.
منابع مشابه
INVESTIGATING THE RELATIONSHIP BETWEEN HEAT OF HYDRATION AND PHYSICO-MECHANICAL PROPERTIES OF CALCIUM SULFATE HEMIHYDRATE IN THE PRESENCE OF ADDITIVES
This article addresses the interplay between heat of hydration and physico-mechanical properties of calcium sulfate hemi-hydrate in the presence of retarding additives such as citric and malic acids and sodium citrate. The heat of hydration was measured using a semi-isothermal calorimeter. Results proved that citric and malic acids had superior impact on hydration and mechanical properties. Whi...
متن کاملCharacterization of spontaneous network-driven synaptic activity in rat hippocampal slice cultures
A particular characteristic of the neonatal hippocampus is the presence of spontaneous network-driven oscillatory events, the so-called giant depolarizing potentials (GDPs). GDPs depend on the interplay between GABA and glutamate. Early in development, GABA, acting on GABAA receptors, depolarizes neuronal membranes via a Cl- efflux. Glutamate, via AMPA receptors, generates a positive feedback n...
متن کاملCharacterization of spontaneous network-driven synaptic activity in rat hippocampal slice cultures
A particular characteristic of the neonatal hippocampus is the presence of spontaneous network-driven oscillatory events, the so-called giant depolarizing potentials (GDPs). GDPs depend on the interplay between GABA and glutamate. Early in development, GABA, acting on GABAA receptors, depolarizes neuronal membranes via a Cl- efflux. Glutamate, via AMPA receptors, generates a positive feedback n...
متن کاملRole of a voltage-sensitive calcium channel blocker on inhibition of apoptosis in sensory neurons of cultured dorsal root ganglia in adult rat
Introduction: Under pathological conditions, abnormal increase in intracellular calcium concentrations is believed to induce cell death. In the present study, a voltage-sensitive calcium channel blocker (loperamide hydrochloride) was used to investigate its role in inhibition of apoptosis in sensory neurons of cultured spinal dorsal root ganglia (DRG). Methods: L5 DRG from adult rats were di...
متن کاملDynamics of Macro–Nano Mechanical Systems; Fixed Interfacial Multiscale Method
The continuum based approaches don’t provide the correct physics in atomic scales. On the other hand, the molecular based approaches are limited by the length and simulated process time. As an attractive alternative, this paper proposes the Fixed Interfacial Multiscale Method (FIMM) for computationally and mathematically efficient modeling of solid structures. The approach is applicable to mult...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Neurocomputing
دوره 70 شماره
صفحات -
تاریخ انتشار 2007